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Research
BCG vaccination-induced emergency granulopoiesis provides rapid protection from neonatal sepsisWe found that BCG, in a mouse model of neonatal polymicrobial sepsis, induced granulocyte colony-stimulating factor (G-CSF) within hours of administration
Research
FeBRILe3 Project: protocol for a prospective study and safety evaluation assessing Fever, Blood cultures and Readiness for discharge in Infants Less than 3 months oldAssess the safety and impact of the introduction of a guideline recommending early discharge of infants with fever without source at low risk of serious bacterial infection
Research
Causes and Clinical Features of Childhood Encephalitis: A Multicenter, Prospective Cohort StudyEpidemic viral infections predominated as causes of childhood encephalitis in Australia. The leading causes include vaccine-preventable diseases
Research
Multi-Omic Data Integration Allows Baseline Immune Signatures to Predict Hepatitis B Vaccine Response in a Small CohortVaccination remains one of the most effective means of reducing the burden of infectious diseases globally. Improving our understanding of the molecular basis for effective vaccine response is of paramount importance if we are to ensure the success of future vaccine development efforts. We applied cutting edge multi-omics approaches to extensively characterize temporal molecular responses following vaccination with hepatitis B virus (HBV) vaccine. Data were integrated across cellular, epigenomic, transcriptomic, proteomic, and fecal microbiome profiles, and correlated to final HBV antibody titres.
Research
Global molecular diversity of RSV – the “INFORM RSV” studyRespiratory syncytial virus (RSV) is a global cause of severe respiratory morbidity and mortality in infants. While preventive and therapeutic interventions are being developed, including antivirals, vaccines and monoclonal antibodies, little is known about the global molecular epidemiology of RSV. INFORM is a prospective, multicenter, global clinical study performed by ReSViNET to investigate the worldwide molecular diversity of RSV isolates collected from children less than 5 years of age.
Research
An international cohort study of birth outcomes associated with hospitalized acute respiratory infection during pregnancyAcute respiratory or febrile illness hospitalization during pregnancy was associated with increased risk of preterm birth and low birthweight birth
Research
Spatial and temporal patterns of dengue incidence in Bhutan: a Bayesian analysisThis study aimed to quantify the spatial and temporal patterns of dengue and their relationship to environmental factors in dengue-affected areas
News & Events
The Kids Research Institute Australia researcher awarded support fundingA Kids Research Institute Australia researcher has been awarded $10,000 from the New Independent Researcher Infrastructure Support (NIRIS) award.
News & Events
Celebrating 20 years of meningitis awarenessAustralian charity celebrates 20 years of providing meningitis awareness and marks World Meningitis Day with footy star
News & Events
Caesarean link to respiratory infections in babiesCaesarean link to respiratory infections in babies