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To assess the effects of topical antiseptics for people with chronic suppurative otitis media
To assess the effects of systemic antibiotics for people with chronic suppurative otitis media.
To assess the effects of topical antibiotics for people with chronic suppurative otitis media.
To assess the effects of adding a topical steroid to topical antibiotics in the treatment of people with chronic suppurative otitis media
These data provide evidence that otitis-prone children do not have impaired functional cell mediated immunity
This Clinical Puzzle article describes our current knowledge of chronic otitis media and the existing research models for this condition
The production of functional antipneumococcal antibodies in otitisprone children demonstrates that they respond to the current pneumococcal conjugate vaccine (PCV)and are likely to respond to pneumolysin-based vaccines as effectively as healthy children.
Otitis media (OM) is a common disease in early childhood characterised by inflammation of the middle ear.
This study was the first to concurrently identify middle ear pathogens in both bacterial biofilm and intracellularly in the middle ear mucosa of children and to identify extensive DNA stranding in the MEF from children with AOM
We identified several novel candidate genes which warrant further analysis in cohorts matched more precisely for clinical phenotypes.