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To assess the effects of topical antiseptics for people with chronic suppurative otitis media
To assess the effectiveness of antibiotics versus antiseptics for people with chronic suppurative otitis media.
These data provide evidence that otitis-prone children do not have impaired functional cell mediated immunity
The production of functional antipneumococcal antibodies in otitisprone children demonstrates that they respond to the current pneumococcal conjugate vaccine (PCV)and are likely to respond to pneumolysin-based vaccines as effectively as healthy children.
The relationship between early life episodes of otitis media and later behavioural development with adjustment for confounders.
PCV10 did not reduce NTHi density in the nasopharynx or middle ear, and was associated with increased pneumococcal nasopharyngeal density
This study was the first to concurrently identify middle ear pathogens in both bacterial biofilm and intracellularly in the middle ear mucosa of children and to identify extensive DNA stranding in the MEF from children with AOM
Identified dominant PCR-ribotypes common to geographically disparate Australian paediatric populations
Our findings are in line with a number of epidemiological studies which show a positive association between breastfeeding and OM in early childhood
Conserved vaccine candidate proteins from S.pneumoniae induce serum and salivary antibody responses in Aboriginal and non-Aboriginal children with history of OM