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Development of the Breastfed Infant Oral Microbiome Is Associated with Concentrations and Intakes of Human Milk Oligosaccharides

Human milk oligosaccharides (HMOs) are bioactive carbohydrates abundant in human milk that shape the infant gut microbiome, yet their influence on the oral microbiome remains poorly understood. This study investigated associations between HMO concentrations and infant HMO intakes and the composition of the oral microbiome in predominantly and exclusively breastfed infants.

Breastfeeding patterns and total volume of human milk consumed influence the development of the infant oral microbiome

The oral microbiome of breastfed infants is distinct from that of formula-fed infants. However, breastfeeding characteristics, such as time spent breastfeeding (min/24 h), breastfeeding frequency (number of breastfeeds per day), and human milk intake (ml/day) vary significantly between breastfeeding dyads.

Breastfeeding

Convenient, readily available and helping create a close and loving bond between baby and mother, breastfeeding is highly regarded for optimising infant health and preventing chronic disease in adulthood.

Maternal Allergic Disease Phenotype and Infant Birth Season Influence the Human Milk Microbiome

Early infancy is a critical period for immune development. In addition to being the primary food source during early infancy, human milk also provides multiple bioactive components that shape the infant gut microbiome and immune system and provides a constant source of exposure to maternal microbiota. Given the potential interplay between allergic diseases and the human microbiome, this study aimed to characterise the milk microbiome of allergic mothers.

Transforming growth factor-Beta in milk

Findings suggest that TGF-Beta in milk may influence the development of immunological outcomes in offspring.

Longer duration of exclusive breastfeeding associated with reduced risk of childhood asthma up to age six

Breastfeeding is recommended for all infants irrespective of atopic heredity, although epidemiological studies provide conflicting results in this debate.

Infant feeding and obesity risk in the child

Early nutrition in infancy may influence later child health outcomes including overweight through 'programming'.

Nutritional supplements during breastfeeding

The aim was to review the use of supplements during lactation and to document the use of nutritional supplements in a cohort of breastfeeding mothers.

Breastfeeding and early child development: A prospective cohort study

Breastfeeding has been associated with multiple developmental advantages for the infant; however, there have also been a number of studies that find...

The effects of breast-feeding duration on language ability to middle childhood

Modern societies are challenged by "wicked problems" - by definition, those that are difficult to define, multi-casual and hard to treat.