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We have revealed a novel SH2D1A gene mutation in a patient with XLP resulting in fulminant refractory EBV-driven HLH, which is a recognized severe complication

Our findings support the hypothesis of a familial susceptibility of childhood brain tumors, not due to being a known neurofibromatosis carrier

We investigated the potential association of maternal coffee and tea consumption during pregnancy with childhood acute myeloid leukemia risk

Early intensification with postinduction myeloid-type chemotherapy courses did not significantly improve outcome for infant acute lymphoblastic leukemia

Our current Research Topic highlights the complexity of the relationship between the skin, immune system and skin cancer

Our results identify a pretreatment tumor microenvironment that predicts response to immune checkpoint blockade, which can be therapeutically attained

In this study, we investigate the in vivo synergy between romidepsin and cytarabine

These findings suggest that tumor cells employ multiple epigenetic and genetic mechanisms to evade immune control

We found two known risk factors in a large cohort of children treated for ALL and identified other factors associated with venous thromboembolism

This systematic review shows that children treated with platinum analogues are at risk of developing hearing loss