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Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and remains one of the most common causes of cancer-related death in children and adolescents. Five-year overall survival rates now exceed 90% with current multidrug chemotherapeutic regimens.

Melanoma, also known as malignant melanoma, occurs when abnormal skin cells multiply rapidly in an uncontrolled way.

Brain tumours are the second most common cancer in children (after leukaemia).

Children with Down syndrome (constitutive trisomy 21) that develop acute lymphoblastic leukemia (DS-ALL) have a 3-fold increased likelihood of treatment-related mortality coupled with a higher cumulative incidence of relapse, compared with other children with B-cell acute lymphoblastic leukemia (B-ALL).

In this investigation, the authors found an association between home pesticide exposure before birth and during a child's early years and acute lymphoblastic...

This paper demonstrated that home paint exposure shortly before conception, during pregnancy, and/or after birth appeared to increase the risk of childhood ALL.

This report provides new insight into the functional specialization within the broad network of dendritic cells that are responsible for skin immunosurveillance

This article summarizes data from collaborative group and institutional trials that have advanced the science of pediatric brain tumors.

We undertook a retrospective review of children diagnosed with acute lymphoblastic leukemia (ALL) and treated with modern COG protocols to determine...

This article investigates the impact of burn & excisional injury on the immune system.