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Fusionfinder: A software tool to identify expressed gene fusion candidates from RNA-seq dataThe hallmarks of many haematological malignancies and solid tumours are chromosomal translocations, which may lead to gene fusions.
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Parental occupational exposure to engine exhausts and childhood brain tumorsChildhood brain tumors (CBT) are the leading cause of cancer death in children; their risk factors are still largely unknown.
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Statistical adjustment of genotyping error in a case-control study of childhood leukaemiaGenotyping has become more cost-effective and less invasive with the use of buccal cell...
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Identification of suitable endogenous control genes for microRNA expression profiling of childhood medulloblastoma and human neural stem cellsMedulloblastoma (MB) is the most common type of malignant childhood brain tumour.
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Novel non-TCR chromosome translocations t(3;11)(q25;p13) and t(X;11)(q25;p13) activating LMO2In T-cell acute lymphoblastic leukemia (T-ALL) cytogenetic alterations juxtapose the LIM-domain-only-2 gene (LMO2) with T-cell receptor loci.
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Maternal folate and other vitamin supplementation during pregnancy and risk of acute lymphoblastic leukemia in the offspringThe Australian Study of Causes of Acute Lymphoblastic Leukemia in Children (Aus-ALL) was designed to test the hypothesis, raised by a previous Western Australia
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Maternal consumption of coffee and tea during pregnancy and risk of childhood ALL: Results from an Australian case-control studyThe objective of this study was to investigate whether maternal coffee and/or tea consumption during the last 6 months of pregnancy was associated with risk...
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Maternal consumption of coffee and tea during pregnancy and risk of childhood ALL: results from an Australian case-control studyTo investigate whether maternal coffee and/or tea consumption during the last 6 months of pregnancy was associated with risk of childhood ALL.
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A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia PathogenesisHere we report that CHAF1B is required for normal hematopoiesis while its overexpression promotes leukemia
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novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunctionThis study thus identified a novel small molecule that rapidly kills MLL-rearranged leukemia cells by targeting a metabolic vulnerability