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Research

Dietary intake and food sources of fatty acids in Australian adolescents

Dietary fat consumed during childhood and adolescence may be related to the development of cardiovascular and other chronic diseases in adulthood.

Research

The role of family and maternal factors in childhood obesity

The aim of this study was to investigate the relationship between a child's weight and a broad range of family and maternal factors.

News & Events

Researcher to plot evolving junk food landscape around every single school in Perth

A The Kids Research Institute Australia researcher will map every food business and school in Perth to investigate the influence of the food environment on children’s food intake and health.

News & Events

Video: Top 6 ways to get your kids to eat their vegies

Nutritionist Dr Roslyn Giglia from The Kids Research Institute Australia shares her top 6 ways to get your kids to eat their vegies.

News & Events

New study shows long term mental health benefits from extended breastfeeding

A new study from Perth's Telethon Institute for Child Health Research has shown that children who are breastfed for longer than six months have a lower risk

News & Events

Researchers investigate childhood diet and teen anxiety and depression link

A study to investigate mental health and dietary patterns throughout childhood and into adolescence has received a $57,800 grant.

Research

Mitochondrial mistranslation modulated by metabolic stress causes cardiovascular disease and reduced lifespan

Changes in the rate and fidelity of mitochondrial protein synthesis impact the metabolic and physiological roles of mitochondria. Here we explored how environmental stress in the form of a high-fat diet modulates mitochondrial translation and affects lifespan in mutant mice with error-prone or hyper-accurate mitochondrial ribosomes. Intriguingly, although both mutations are metabolically beneficial in reducing body weight, decreasing circulating insulin and increasing glucose tolerance during a high-fat diet, they manifest divergent (either deleterious or beneficial) outcomes in a tissue-specific manner.

Research

Endocrine and metabolic consequences due to restrictive carbohydrate diets in children with type 1 diabetes: An illustrative case series

We describe a series of 6 cases where adoption of a low carbohydrate diet in children impacted growth and cardiovascular risk factors with potential long-term sequelae.

Research

Breastfeeding and motor development: A longitudinal cohort study

Early life feeding practices have an influence on motor development outcomes into late childhood and adolescence independent of sociodemographic factors

Research

Prebiotic Supplementation During Pregnancy Modifies the Gut Microbiota and Increases Metabolites in Amniotic Fluid, Driving a Tolerogenic Environment In Utero

The gut microbiota is influenced by environmental factors such as food. Maternal diet during pregnancy modifies the gut microbiota composition and function, leading to the production of specific compounds that are transferred to the fetus and enhance the ontogeny and maturation of the immune system. Prebiotics are fermented by gut bacteria, leading to the release of short-chain fatty acids that can specifically interact with the immune system, inducing a switch toward tolerogenic populations and therefore conferring health benefits.