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CFTR-dependent defect in alternatively-activated macrophages in cystic fibrosis

CFTR-dependent imbalance of macrophage phenotypes and functions could contribute to the exaggerated inflammatory response seen in CF lung disease

The WHF Roadmap for Reducing CV Morbidity and Mortality Through Prevention and Control of Rheumatic Heart Disease

As a general guide, the Roadmap is meant to serve as the foundation for the development of tailored plans of action to improve RHD control in specific contexts.

Interferon regulatory factor 7 regulates airway epithelial cell responses to human rhinovirus infection

IRF7 regulates the expression of genes involved in antiviral immunity, inflammation, and the response to oxidative stress during HRV infections in HBE cells

Prevention of Allergy/Asthma - New Strategies

This review focuses on the scientific rationale for early intervention aimed at asthma prophylaxis and discusses therapeutic approaches

New focus on type 2 diabetes

Researchers at the Children’s Diabetes Centre at The Kids Research Institute Australia have begun researching type 2 diabetes to tackle the rising incidence of the disease among young people in Australia.

Oxidative cross-linking of calprotectin occurs in vivo, altering its structure and susceptibility to proteolysis

Oxidative cross-linking of calprotectin occurs in vivo, altering its structure and susceptibility to proteolysis Abstract Calprotectin, the major

Use of a Primary Epithelial Cell Screening Tool to Investigate Phage Therapy in Cystic Fibrosis

Use of a Primary Epithelial Cell Screening Tool to Investigate Phage Therapy in Cystic Fibrosis Antimicrobial-resistant microbes are an increasing

Workplace giving

Workplace Giving to The Kids Research Institute Australia is a fantastic way to engage staff and contribute towards ensuring all kids have a happy healthy childhood.

Healthy Lungs & Immune Development

Focusing on the developmental trajectories of respiratory health includes developing strategies to improve and support immune system function and development over the life course.