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This review explores computational strategies to yield biological insight into the processes involved in the immunotherapeutic response

This study thus identified a novel small molecule that rapidly kills MLL-rearranged leukemia cells by targeting a metabolic vulnerability

The ANZCHOG-BN was developed to improve and streamline access to high quality pediatric and adolescent/young adult cancer biospecimens for cancer research

We discovered a previously unknown major resistance mechanism in glioma in that most EGFR domain III-targeting antibodies do not neutralize EGFRvIII

We present a curated panel of 12 readily-usable, cell lines representing the spectrum of molecular subtypes of IDH-wildtype glioblastoma

Bevacizumab is well tolerated and appears most effective for rapid tumor control to preserve vision and improve morbidity

This multi-center study provides valuable information on the success rate of establishing patient-derived pre-clinical models of diffuse intrinsic pontine glioma

This chapter summarizes recent advances in diffuse intrinsic pontine glioma and potential novel therapies

We provide evidence that targeting leukemia-induced bone loss is a therapeutic strategy for pre-B ALL

Here we report that CHAF1B is required for normal hematopoiesis while its overexpression promotes leukemia