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Epigenome-wide meta-analysis of DNA methylation and childhood asthma

Novel loci differentially methylated in newborns represent potential biomarkers of risk of asthma by school age

Bronchodilator responsiveness in children with asthma is not influenced by spacer device selection

Spacer device was not associated with clinically important differences in lung function following bronchodilator inhalation in children with asthma

Triage phone service

Did you know that we now have a 'triage' section on the DiabHQ app with useful documents and a FAQs page.

Service availability

Are you tired of being on waitlists to access supports for your family? CliniKids has immediate availability for a number of therapies and programs in clinic (Subiaco and Joondalup) or via telehealth.

Upper Airway Cell Transcriptomics Identify a Major New Immunological Phenotype with Strong Clinical Correlates in Young Children with Acute Wheezing

Asthma exacerbations in children can be divided into IRF7hi versus IRF7lo phenotypes with associated differences in clinical phenotypes

Children with East Asian-Born Parents Have an Increased Risk of Allergy but May Not Have More Asthma in Early Childhood

Children of East Asian ancestry born in Australia have a higher burden of most allergic diseases in the first 6 years of life, whereas asthma may follow a different pattern

Cessation of Courier Service

ORIGINS is no longer offering courier services or home collection of samples.

Risk factors for bronchial hyperresponsiveness in teenagers differ with sex and atopic status

Sex-related differences in bronchial hyperresponsiveness (BHR) have been reported in adolescents, but the mechanisms remain obscure.

Project websites

These project websites display extended detailed information about specific research areas.

Defective function at the epithelial junction: A novel therapeutic frontier in asthma?

The airway epithelium forms a highly regulated physical barrier that normally prevents invasion of inhaled pathogens and allergens from the airway lumen.

Purpose After Service through Sport (PASS): Supporting Military Veterans and their Families

Veterans who transition out of the military often face substantive challenges during their move to civilian life, including the management of their health, identifying opportunities for employment, contributing to the financial and emotional functioning of their household, and developing high-quality social connec

Interaction between adaptive and innate immune pathways in the pathogenesis of atopic asthma: Operation of a lung/bone marrow axis

Atopic asthma is the most common form of asthma, particularly during childhood, and in many cases it persists into adult life.

Service use

Parents and carers reported on the health, school, telephone counselling and online services used by young people, as well as any medication taken.

Vitamin D and atopy and asthma phenotypes in children: a longitudinal cohort study

Vitamin D has been linked in some studies with atopy- and asthma-associated phenotypes in children with established disease,but its role in disease inception...

Service agreements

We are currently working through several clinical audits to ensure that we are meeting our service delivery standards and governance requirements. As part of this, we have audited our Service Agreements to ensure that we have a signed agreement on file for all our clients. This agreement is an NDIS

Two newly identified cat allergens: The von Ebner gland protein Fel d 7 and the latherin-like protein Fel d 8

Characterization of the complete IgE binding spectrum of cat allergens is important for the development of improved diagnosis and effective immunotherapeutics.

Regulatory role of IL10 genetic variations in determining allergen-induced TH2 cytokine responses in children

Interleukin-10 is a key immunomodulatory cytokine the principal function of which is to limit the magnitude of immune response.

Biospecimen Service

BioSpecs is a flexible service that supports laboratory research by providing expert technical assistance in pre-analytical sample processing and nucleic acid extractions.

Aged care service use by Aboriginal and Torres Strait Islander people after aged care eligibility assessments, 2017–2019: a population-based retrospective cohort study

To characterise the socio-demographic characteristics, aged and health care needs, and aged care services used by older Aboriginal and Torres Strait Islander people assessed for aged care service eligibility.

Suicide prevention in LGBTQA+ young people: Best practice guidelines for clinical and community service providers

These guidelines outline a set of best practices for suicide prevention in LGBTQA+ young people, targeting both clinical and community service providers.