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Vincristine sulphate, a microtubule inhibitor, is used extensively in veterinary oncology for treating lymphoma. Neutropenia during multiagent protocols is a common reason for treatment delay and reduced dose intensity. This study evaluated toxicities associated with treating systemically well neutropenic lymphoma patients with vincristine.

Each year, approximately 1000 children in Australia and New Zealand, aged 0–14 years, are diagnosed with cancer. Despite paediatric cancer accounting for less than 1% of all cancer cases, the impact on their families and communities is profound and disproportionate.

We provide evidence that targeting leukemia-induced bone loss is a therapeutic strategy for pre-B ALL

Despite low ERBB4 mRNA in glioblastoma, the functional effects of increased ERBB4 activation identify ERBB4 as a potential prognostic and therapeutic target

These findings provide a compelling argument for efforts to reduce exposure of the brainstem in the treatment of medulloblastoma

Medulloblastoma is a highly malignant small round blue cell tumor of the posterior fossa

This chapter summarizes recent advances in diffuse intrinsic pontine glioma and potential novel therapies

The functional effects of increased ERBB4 activation identify ERBB4 as a potential prognostic and therapeutic target

These findings add additional evidence to the hypothesis that regular contact with animals in early childhood is inversely associated with childhood acute lymphoblastic leukemia

This study demonstrates that exercise is achievable and has positive effects on vascular function, submaximal fitness, local strength and physical activity in a population of AYA survivors of pediatric oncology related cerebral insult