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OMIP-100: A flow cytometry panel to investigate human neutrophil subsetsThis 14-color, 13-antibody optimized multicolor immunofluorescence panel (OMIP) was designed for deep profiling of neutrophil subsets in various types of human samples to contextualize neutrophil plasticity in a range of healthy and diseased states. Markers present in the OMIP allow the profiling of neutrophil subsets associated with ontogeny, migration, phagocytosis capacity, granule release, and immune modulation.
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Volatiles or TIVA: Which is the standard of care for pediatric airway procedures? A pro-con discussionThis pro-con discussion examines both volatiles and TIVA, from the perspective of effectiveness, safety, cost, and environmental impact,
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Bronchiectasis Research for Improving Lung Health outcomes and Treatment (BRIGHT)This prospective, longitudinal cohort study will examine airway sputum, lung function, and clinical surveillance data of children with bronchiectasis attending Perth Children’s Hospital.
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Effects of adopting the new global lung function initiative 2012 reference equations on the interpretation of spirometryThe aim of this study was to document the likely interpretative effects of changing from commonly used current spirometry reference equations to the GLI2012...
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Novel end points for clinical trials in young children with cystic fibrosisCystic fibrosis (CF) lung disease commences early in the disease progression and is the most common cause of mortality.
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Early detection of lung function abnormalities in young children with cystic fibrosisIn this review, we have examined the role of lung function testing in infants and preschool children with CF.
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Oscillometry: clinical significance and applicationsRespiratory oscillometry (or the forced oscillation technique) is a highly practical lung function test that can be applied in a wide range of clinical scenarios in children and adults, including the clinic, intensive care unit, patient home monitoring and emergency departments. Oscillometry measurements complement spirometry in detecting abnormal lung function, measuring effects of treatment such as inhaled corticosteroids or bronchodilators, and changes due to disease activity.
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Prevalence of chronic wet cough and protracted bacterial bronchitis in aboriginal childrenStrategies to address reasons for and treatment of chronic wet cough and protracted bacterial bronchitis in young Aboriginal children in remote north Western Australia are required
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Is forced oscillation technique the next respiratory function test of choice in childhood asthmaWhile spirometry contributes to asthma diagnosis and management in older children, it has a limited role in younger children whom are unable to perform FOM.