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Functional role of CTGF in altering disease progression in a lymphoid malignancy
Biological changes associated with T-ALL relapse and resistance are stochastic and highly individual
Identified CCI-007 as a novel small molecule that displays rapid toxicity towards a subset of MLL-r, CALM-AF10 and SET-NUP214 leukemia cell lines
In this investigation, the authors found an association between home pesticide exposure before birth and during a child's early years and acute lymphoblastic...
This paper demonstrated that home paint exposure shortly before conception, during pregnancy, and/or after birth appeared to increase the risk of childhood ALL.
This report provides new insight into the functional specialization within the broad network of dendritic cells that are responsible for skin immunosurveillance
This article summarizes data from collaborative group and institutional trials that have advanced the science of pediatric brain tumors.
Children with Down syndrome (constitutive trisomy 21) that develop acute lymphoblastic leukemia (DS-ALL) have a 3-fold increased likelihood of treatment-related mortality coupled with a higher cumulative incidence of relapse, compared with other children with B-cell acute lymphoblastic leukemia (B-ALL).
IL7 and glucocorticoids coordinately drive aberrant activation of PIM1 and suggests that T-ALL and T-LBL patients could benefit from PIM inhibition
Development of standardised guidance by national and regional authorities for reducing the risk of SARS-CoV-2 transmission to children with cancer