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Research

B cell epitope mapping: The journey to better vaccines and therapeutic antibodies

B-cell epitope mapping is an approach that can identify and characterise specific antigen binding sites of B-cell receptors and secreted antibodies. The ability to determine the antigenic clusters of amino acids bound by B-cell clones provides unprecedented detail that will aid in developing novel and effective vaccine targets and therapeutic antibodies for various diseases.

Research

The complement system in systemic lupus erythematosus: An update

The complement system plays a major role in the autoimmune disease, systemic lupus erythematosus (SLE). This review highlights the many roles of complement for

Research

Real-time safety surveillance of seasonal influenza vaccines in children, Australia, 2015

This paper reports the results from the safety surveillance of influenza vaccines in children in Australia, in 2015.

The SYMBA Study

SYMBA is promoting gut health (symbiosis) with prebiotic fibre taken during pregnancy for prevention of allergic disease.

The PLAN Project

Pregnancy Lifestyle Activity and Nutrition (PLAN)

The SYMBA Study

SYMBA is promoting gut health (symbiosis) with prebiotic fibre taken during pregnancy for prevention of allergic disease.

Research

Immunotherapy of allergic diseases by bacterial products

Allergic diseases are characterized by excessive immunoglobulin E (IgE) production, mast cell degranulation, tissue eosinophilia and mucus hypersecretion

Research

Acute lower respiratory infections (ALRI) in Indigenous and non-Indigenous children

In Australia and many other developed countries, acute lower respiratory infection (ALRI) is one of the most common reasons for hospitalisation in young...

Research

Caudal dysgenesis and sirenomelia-single centre experience suggests common pathogenic basis

Abnormally formed lower limbs with varying degrees of fusion are the major feature of sirenomelia whereas maldeveloped lower limbs without fusion are found in a