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Myositis complicating benzathine penicillin-G injection in a case of rheumatic heart diseaseA 7-year old boy developed myositis secondary to intramuscular injection of benzathine penicillin-G in the context of secondary prophylaxis for RF
Research
Acute rheumatic fever and rheumatic heart diseaseAcute rheumatic fever (ARF) is the result of an autoimmune response to pharyngitis caused by infection with group A Streptococcus.
Research
Development of Group A streptococcal vaccines: an unmet global health needThis review provides an update on the current status of Group A Streptococcus vaccine development, & describes global efforts to accelerate the development...
Research
The case for global investment in rheumatic heart-disease controlThe review built a case for extending simple and cost–effective measures to all countries. Had these recommendations been put into action, significant...
Research
Progress toward a global Group A streptococcal vaccineThe desire for an effective vaccine arises from the large burden of disease caused by the bacterium, particularly rheumatic fever and rheumatic heart disease.
Research
Group A streptococcal vaccines: Paving a path for accelerated developmentVaccine prevention of GAS infections and their immunological complications has been a goal of researchers for decades.
News & Events
Call for Group A streptococcal infections to become notifiable diseasesResearchers at The Kids Research Institute Australia say Group A Streptococcus should become a nationally notifiable disease in Australia.
Research
Primary prevention of acute rheumatic feverAcute rheumatic fever (ARF) is an abnormal immune reaction following Streptococcus pyogenes (Strep A) infection of the throat, and likely the skin. Primary prevention is the prompt and appropriate antibiotic treatment of Strep A infection, and it can reduce the risk of developing ARF and subsequent rheumatic heart disease.
Research
Incidence of acute rheumatic fever in northern and western Uganda: a prospective, population-based studyAcute rheumatic fever is infrequently diagnosed in sub-Saharan African countries despite the high prevalence of rheumatic heart disease. We aimed to determine the incidence of acute rheumatic fever in northern and western Uganda.
Research
Outcomes of latent rheumatic heart disease: External validation of a simplified score in patients with and without secondary prophylaxisSecondary antibiotic prophylaxis reduces progression of latent rheumatic heart disease (RHD) but not all children benefit. Improved risk stratification could refine recommendations following positive screening. We aimed to evaluate the performance of a previously developed echocardiographic risk score to predict mid-term outcomes among children with latent RHD.Â