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Research

Early motor function of children with autism spectrum disorder: A systematic review

Early motor impairments have been reported in children with neurodevelopmental disorders (NDD), but it is not clear if early detection of motor impairments can identify children at risk for NDD or how early such impairments might be detected. Our aim was to characterize early motor function in children later diagnosed with NDD relative to typically developing children or normative data.

Research

Subgroups of Temperament Associated with Social-Emotional Difficulties in Infants with Early Signs of Autism

Links between temperament and social-emotional difficulties are well-established in normative child development but remain poorly characterized in autism. We sought to characterize distinct temperament subgroups and their associations with concurrent internalizing and externalizing symptoms in a sample of 103 infants showing early signs of autism.

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A broad autism phenotype expressed in facial morphology

These data provide the first evidence for a broad autism phenotype expressed in a physical characteristic

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Increased facial asymmetry in autism spectrum conditions is associated with symptom presentation

Significantly greater depth-wise facial asymmetry was identified in autistic children relative to the two comparison groups

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An integrative analysis of non-coding regulatory DNA variations associated with autism spectrum disorder

Overall, we found that the regulatory variants in autism spectrum disorder cases were enriched in ASD-risk genes and genes involved in fetal neurodevelopment

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Parent-observed thematic data on quality of life in children with autism spectrum disorder

Parent observations provide an initial framework for understanding quality of life in autism spectrum disorder

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Measuring the capacity of active video games for social interaction: The Social Interaction Potential Assessment tool

The Social Interaction Potential Assessment tool can assess Active Video Games potential to facilitate social interaction among players

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Study protocol for the Australian autism biobank: an international resource to advance autism discovery research

The Australian Autism Biobank was initiated to establish a large-scale repository of biological samples and detailed clinical information about children diagnosed with ASD

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Attenuated psychophysiological reactivity following single-session group imagery rescripting versus verbal restructuring in social anxiety disorder

The current study highlights the specificity of brief imagery-based interventions in influencing psychophysiological reactivity in social anxiety disorder

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Evidence of a reduction over time in the behavioral severity of autistic disorder diagnoses

We examined whether there were changes over time in the qualitative and quantitative phenotype of individuals who received the diagnosis of Autistic Disorder.