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Boosting the influenza vaccine schedule in children with cancer: a prospective open-label studyCurrent immunization guidelines recommend one dose of influenza vaccine for children aged ≥9 years and two doses for younger or vaccine-naïve children. However, children receiving chemotherapy have an attenuated immune response. We performed a prospective open-label study in children undergoing treatment for cancer at Perth Children's Hospital, Western Australia, to examine the safety and efficacy of a boosted influenza schedule.
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Immunogenicity and Safety of a 2 + 1 DTPa Priming Schedule in Australian Infants and the Impact of Maternally Derived Antibodies on Pertussis Antibody Responses up to 4 Years of AgeWe assessed the impact of maternally derived pertussis antibodies on infant responses to a 2 + 1 vaccine schedule (6 weeks, 12 weeks, and 12 months). Infants with baseline antibodies showed lower IgG responses following the primary vaccination series, but this did not impair booster responses at 4 years of age.
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A comprehensive evaluation of a two-channel portable monitor to "rule in" obstructive sleep apneaWe hypothesized that a dual-channel portable monitor (PM) device could accurately identify patients who have a high pretest probability of obstructive sleep...
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Parental prenatal smoking and risk of childhood Acute Lymphoblastic LeukemiaThe association between parental smoking and risk of childhood acute lymphoblastic leukemia (ALL) was investigated in an Australian population-based...
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Umbilical Cord Blood Testosterone and Childhood Internalizing and Externalizing Behavior: A Prospective StudyAntenatal testosterone exposure influences fetal neurodevelopment and gender-role behavior in postnatal life and may contribute to differences in...
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High prevalence of undiagnosed obstructive sleep apnoea in the general population and methods for screening for representative controlsUndiagnosed obstructive sleep apnoea (OSA) in the community makes comparisons of OSA subjects with control samples from the general population problematic.
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Energy drink consumption is associated with anxiety in australian young adult malesEnergy drinks are predominantly targeted to young adult consumers; however, there has been limited research into their effects on psychological functioning...
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Changes in risk factors for preterm birth in Western Australia 1984-2006Marked increases in maternal age and primiparous births were observed. A four-fold increase in the rates of pre-existing medical complications over time...
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Emergency department overcrowding, mortality and the 4-hour rule in Western AustraliaThe objective of this study was to assess whether emergency department (ED) overcrowding was reduced after the introduction of the 4-hour rule in WA hospitals.
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Persistent Effects of Maternal Smoking during Pregnancy on Lung Function and Asthma in AdolescentsThe extent to which maternal smoking in pregnancy (MSP) has persisting effects on respiratory health remains uncertain and the mechanisms involved are not...