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Research
Verschlimmbesserung: Craniospinal Radiotherapy Is Essential in WNT Medulloblastoma PatientsStandard-risk WNT medulloblastoma patients have an excellent prognosis using the combination of standard dose craniospinal radiotherapy (CSI) followed by platinum and alkylator based chemotherapy. A recent pilot study that attempted to completely omit radiotherapy was terminated early as all patients relapsed rapidly. The study highlights that therapy is the most important prognostic factor, with CSI still required to cure even the most favorable subgroup of medulloblastoma patients.
Research
Intravascular Tumor Extension and Pulmonary Tumor Embolism in Children With Solid Malignancies: Is There a Role for Inferior Vena Cava Filters?Intravascular tumor extension is an uncommon complication of solid malignancies that, when present in the inferior vena cava (IVC), can result in fatal pulmonary tumor embolism. Currently, neoadjuvant chemotherapy and surgery are the mainstays of treatment; however, there are no consensus guidelines for management.
Research
Insights into the Clinical, Biological and Therapeutic Impact of Copy Number Alteration in CancerCopy number alterations (CNAs), resulting from the gain or loss of genetic material from as little as 50 base pairs or as big as entire chromosome(s), have been associated with many congenital diseases, de novo syndromes and cancer. It is established that CNAs disturb the dosage of genomic regions including enhancers/promoters, long non-coding RNA and gene(s) among others, ultimately leading to an altered balance of key cellular functions.
Research
Exposure to diagnostic radiological procedures and the risk of childhood acute lymphoblastic leukemiaDiagnostic irradiation of the mother during pregnancy increases the risk of childhood acute lymphoblastic leukemia
News & Events
WA Child Research Fund grants boost research for premmies, kids with cancer and rare diseasesThe Kids Research Institute Australia researchers have been awarded 12 of 16 grants under the latest round of funding from the WA Child Research Fund
News & Events
Ethan's brain cancer battle inspires researchA new research scholarship to combat childhood brain tumours will be launched tonight in honour of two year old Perth toddler Ethan Davies.
News & Events
World-first clinical trial in ‘man’s best friend’ could unlock treatment breakthrough for kids with cancerThe Kids Research Institute Australia is leading a unique clinical trial in pet dogs that could pave the way for a new immunotherapy treatment for one of the most common childhood cancers, Sarcoma.
News & Events
Trial of new antibody gives hope to children suffering from brain cancerChildren with aggressive brain cancers could soon have access to a significant new treatment option, using a unique antibody that stops cancer cells from repairing themselves.
News & Events
The Kids Research Institute Australia Cancer Centre Researcher wins Cancer Council WA FellowshipCancer Council WA has awarded a Post-Doctoral Fellowship to Dr Ben Wylie, for his project to help kids with sarcoma.
News & Events
“Natural killer” donor cells fighting kids leukaemiaNew research by The Kids shows donor immune cells are highly effective at boosting the body’s response against leukaemia.