The effect of breast-feeding on the development of allergic disease is uncertain
Atopic asthma is the most common form of asthma, particularly during childhood, and in many cases it persists into adult life.
An improved understanding of the roles of protein kinases in intracellular signalling and disease progression has driven significant advances in prot…
Interleukin-10 is a key immunomodulatory cytokine the principal function of which is to limit the magnitude of immune response.
The hallmark of atopic asthma is transient airways hyperresponsiveness (AHR) preceded by aeroallergen-induced Th-cell activation.
Pulmonary function measures reflect respiratory health and are used in the diagnosis of chronic obstructive pulmonary disease.
Childhood asthma is a condition characterized by airflow obstruction that varies in time spontaneously, in response to various environmental stimuli.…
Airway epithelial cells act through multiple mechanisms to function as an important component of the pulmonary defence strategy that is crucial...
For 20 years, the hygiene hypothesis has dominated attempts to explain the increasing prevalence of allergic disease. A causal link between maternal…
Elucidation of early life factors is critical to understand the development of allergic diseases, especially those manifesting in early life such as…