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Increased CTLA-4+ T cells may contribute to impaired T helper type 1 immune responses in patients with chronic obstructive pulmonary diseaseChronic inflammation may expand sub-populations of T cells expressing CTLA-4 in COPD patients and therefore impair T-cell function
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Transcriptome Analysis Uncovers a Growth-Promoting Activity of Orosomucoid-1 on HepatocytesOrm1 is induced in response to hepatic injury and executes liver regeneration by activating cell cycle progression in hepatocytes
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Relationship between out-of-home care placement history characteristics and educational achievement: A population level linked data study.This study examined the influence of placement stability, reunification, type of care, time in care and age at entry to care on children's educational outcomes.
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New Opportunities for Evidence in Fetal Alcohol Spectrum DisorderRecent research, using objective 3-dimensional facial imaging, has found differences between the facial shape of individuals with FAS and the facial shape of individuals without FAS or with partial FAS
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Cancer incidence in the Western Australian mining industryWorking underground emerged as a significant determinant of lung cancer risk in our contemporary mining cohort
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Vaccine hesitancy, refusal and access barriers: The need for clarity in terminologyWe propose more precision in the term 'vaccine hesitancy' is needed particularly since much under-vaccination arises from factors related to access
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Atopy-dependent and independent immune responses in the heightened severity of atopics to respiratory viral infections: Rat model studiesThe co-exposure responses in the Th2high BN incorporated type I interferon/Th1, alternative macrophage activation/Th2 and Th17 signatures
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Predicting language difficulties in middle childhood from early developmental milestones: A comparison of traditional regression and machine learning techniquesThe current study provides preliminary evidence that machine learning algorithms provide equivalent predictive accuracy to traditional methods for language difficulties in middle childhood
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A profile of social, separation and generalized anxiety disorders in an Australian nationally representative sample of children and adolescentsSocial, separation and generalized anxiety disorders in young people are relatively common and impairing, with a high level of comorbidity
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Prediction models for the development of COPD: A systematic reviewWe aimed to systematically review and assess the performance of all published models that predicted development of COPD