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Cystic fibrosis is an inherited condition that results in chronic lung disease. In recent years, a new type of medication called CFTR modulators has become available.
This research project will investigate the traits of preterm lung disease, looking into the long-term lung health of children born preterm, aiming to identify traits that could help guide better treatments in the future.
This prospective, longitudinal cohort study will examine airway sputum, lung function, and clinical surveillance data of children with bronchiectasis attending Perth Children’s Hospital.
Senior Research Fellow
Honorary Research Associate
Co-Head, Foundations of Lung Disease
Head, Strong Beginnings Research, Co-head Foundations of Lung Disease
Bronchiectasis is a chronic lung disease that impairs quality of life and reduces life expectancy.
People born preterm (<37 weeks’ gestation) have lower peak oxygen consumption (peak VO2), a well-established indicator of long-term health outcomes, compared to term-born peers. However, responses to exercise can vary with exercise mode, which has implications for prognostic assessments.
Clinical utility of home polysomnography in children with neuromuscular disorders is limited by lack of evidence that sleep-disordered breathing can be reliably identified and inability to diagnose hypoventilation because carbon dioxide is not measured.