Search

The class 1A aldehyde dehydrogenase (ALDH1A) subfamily of genes encode enzymes that function at the apex of the retinoic acid (RA) signalling pathway.

Complement receptor 2 (CR2/CD21) plays an important role in the generation of normal B cell immune responses.

Medulloblastoma is the most common form of malignant paediatric brain tumour and is the leading cause of childhood cancer related mortality.

Connective tissue growth factor (CTGF/CCN2) has long been associated with human cancers. The role it plays in these neoplasms is diverse and tumour specific.

Despite initial improvements in survival of infants with ALL since establishment of the first pediatric cooperative group ALL trials, the poor outcome has...

Although neurocognitive, psychological and behavioural problems were noted for some patients during medical review, only 20% of patients were formally assessed.

This study advances our understanding of drug resistance in T-ALL and provides new markers for patient stratification.

This study contributes to our understanding of the genetic diversity of NMC, an important step towards finding therapeutic targets for a disease that is...

Acute Lymphoblastic Leukemia (ALL) occurring in the first year of life is rare.

The hallmarks of many haematological malignancies and solid tumours are chromosomal translocations, which may lead to gene fusions.