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The seven key challenges summarized in this Position Paper are intended to serve as foci for future research and investment in brain tumours

The ANZCHOG-BN was developed to improve and streamline access to high quality pediatric and adolescent/young adult cancer biospecimens for cancer research

We discovered a previously unknown major resistance mechanism in glioma in that most EGFR domain III-targeting antibodies do not neutralize EGFRvIII

Bevacizumab is well tolerated and appears most effective for rapid tumor control to preserve vision and improve morbidity

This multi-center study provides valuable information on the success rate of establishing patient-derived pre-clinical models of diffuse intrinsic pontine glioma

This chapter summarizes recent advances in diffuse intrinsic pontine glioma and potential novel therapies

This study demonstrates that exercise is achievable and has positive effects on vascular function, submaximal fitness, local strength and physical activity in a population of AYA survivors of pediatric oncology related cerebral insult

We describe the case of a child with a right 11th rib primitive neuroectodermal tumor who developed HSOS following focal radiotherapy and actinomycin-D treatment

These findings provide a compelling argument for efforts to reduce exposure of the brainstem in the treatment of medulloblastoma

Despite low ERBB4 mRNA in glioblastoma, the functional effects of increased ERBB4 activation identify ERBB4 as a potential prognostic and therapeutic target