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Sex-based differences in long-term lipid metabolism, inflammation, and stress regulation after non-severe paediatric burns

Paediatric burn injuries are a global health concern with long-term health consequences, such as psychological, immune, and cardiovascular complications, that can persist even after non-severe injuries. Emerging evidence suggests that biological sex may influence post-burn outcomes in children, as female burn survivors have been shown to experience higher mortality, scarring, anxiety, depression, and poorer quality of life compared to males. 

Urinary Ferritin as a Noninvasive Means of Assessing Iron Status in Young Children

Iron deficiency (ID) is the most common nutritional deficiency affecting young children. Serum ferritin concentration is the preferred biomarker for measuring iron status because it reflects iron stores; however, blood collection can be distressing for young children and can be logistically difficult. A noninvasive means to measure iron status would be attractive to either diagnose or screen for ID in young children.

Retrospective Examination of Peripubertal Return for Patients of Western Australia's Gender Diversity Service

Children far in advance of pubertal development may be deferred from further assessment for gender-affirming medical treatment until nearer puberty. It is vital that returning peripubertal patients are seen promptly to ensure time-sensitive assessment and provision of puberty suppression treatment where appropriate.

Influence of maternal and infant technology use and other family factors on infant development

Steve Desiree Zubrick Silva FASSA, FAAMHS, MSc AM PhD MBBS, FRACP, MPH, PhD Honorary Emeritus Research Fellow Co-Director, ORIGINS 08 6319 1409

Metagenomic Characterisation of the Gut Microbiome and Effect of Complementary Feeding on Bifidobacterium spp. in Australian Infants

Complementary feeding induces dramatic ecological shifts in the infant gut microbiota toward more diverse compositions and functional metabolic capacities, with potential implications for immune and metabolic health. The aim of this study was to examine whether the age at which solid foods are introduced differentially affects the microbiota in predominantly breastfed infants compared with predominantly formula-fed infants. 

Gut microbiome and innate immune response patterns in IgE-associated eczema

Gut microbiome patterns have been associated with predisposition to eczema potentially through modulation of innate immune signalling.

Maternal fish oil supplementation in pregnancy: a 12 year follow-up of a randomised controlled trial.

We aimed to investigate the long-term effects (12 years) of fish oil supplementation in pregnancy on neurodevelopment, including cognition, language and fine...

The maturation of immune functions in pregnancy and early childhood

This book chapter explains the maturation of immune functions during pregnancy & in early childhood, and addresses the importance of early environmental...

Prevention and Natural History of Food Allergy

The rise in food allergy is more rapid than genetic deviation would allow and the current consensus is that environmental factors integrally linked to the...

Developing primary intervention strategies to prevent allergic disease

Allergic diseases are a major cause of morbidity in the developed world, now affecting up to 40 % of the population with no evidence that this is abating.