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Switch on the immune system early

Findings by Professor Pat Holt revealed researchers had been heading down the wrong path in their battle strategy against respiratory allergy and asthma.

Overseas trip will help unlock the asthma puzzle

One in ten Australians have asthma and Dr Kimberley Wang from The Kids Research Institute Australia is on a mission to find out what causes it.

Healthy lungs, healthy life

The lungs are one of the last organs in the body to develop as a baby grows. They're also one of the most important.

Research reveals new link between Vitamin D, lung bacteria and asthma

A The Kids for Child Health Research study has uncovered a new link between vitamin D levels and asthma.

Call for mental health support for kids with asthma

A new study has found that young children with severe or persistent asthma are at higher risk of developing many common mental health problems.

Volunteers needed for world-first trial to prevent asthma

Australian scientists have today launched a world first research trial into a treatment that could prevent asthma in high risk children.

Chance to prevent asthma missed

Two Australian scientists are spearheading an international campaign that's challenging the way asthma drugs are developed and tested.

Respiratory infection- and asthma-prone, low vaccine responder children demonstrate distinct mononuclear cell DNA methylation pathways

nfants with frequent viral and bacterial respiratory infections exhibit compromised immunity to routine immunizations. They are also more likely to develop chronic respiratory diseases in later childhood. This study investigated the feasibility of epigenetic profiling to reveal endotype-specific molecular pathways with potential for early identification and immuno-modulation. 

Oscillometry: clinical significance and applications

Respiratory oscillometry (or the forced oscillation technique) is a highly practical lung function test that can be applied in a wide range of clinical scenarios in children and adults, including the clinic, intensive care unit, patient home monitoring and emergency departments. Oscillometry measurements complement spirometry in detecting abnormal lung function, measuring effects of treatment such as inhaled corticosteroids or bronchodilators, and changes due to disease activity.

Adipose tissue in the small airways: How much is enough to drive functional changes?

Obesity is a contributing factor to asthma severity; while it has long been understood that obesity is related to greater asthma burden, the mechanisms though which this occurs have not been fully elucidated. One common explanation is that obesity mechanically reduces lung volume through accumulation of adipose tissue external to the thoracic cavity.