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Research

Maternal, umbilical cord and neonatal inflammatory and hematologic markers in histologic chorioamnionitis

Maternal, umbilical cord, neonatal inflammatory, hematologic markers, histologic chorioamnionitis...

Research

Birth order and childhood type 1 diabetes risk: A pooled analysis of 31 observational studies

Background: The incidence rates of childhood onset type 1 diabetes are almost universally increasing across the globe but the aetiology of the disease...

Research

Variants near CCNL1/LEKR1 and in ADCY5 and Fetal Growth Characteristics in Different Trimesters

A recent genome-wide association study identified variants near CCNL1/LEKR1 (rs900400) and in ADCY5 (rs9883204) to be associated with birth weight.

Research

Soluble Glycoprotein VI Is Raised in the Plasma of Patients With Acute Ischemic Stroke

schemic stroke induced by thrombosis may be triggered by atherosclerotic plaque rupture and collagen-induced platelet activation. Collagen induces...

Research

Examining ERBB2 as a candidate gene for susceptibility to leprosy (Hansen's disease) in Brazil

This study examines whether polymorphisms in the ERBB2 gene were associated with leprosy in primary and replication cohorts from northeastern Brazil.

Research

A Genome-Wide Search for Type 2 Diabetes Susceptibility Genes in an Extended Arab Family

We performed a discovery GWAS in an extended UAE family (N = 178; 66 diabetic; 112 healthy) genotyped on the Illumina Human 660 Quad Beadchip, with...

Research

Utility of auscultatory screening for detecting rheumatic heart disease in high-risk children in Australia's Northern Territory

Sensitivity and positive predictive value of cardiac auscultation compared with echocardiography is poor, regardless of the expertise of the auscultator.

Research

Effects of adopting the new global lung function initiative 2012 reference equations on the interpretation of spirometry

The aim of this study was to document the likely interpretative effects of changing from commonly used current spirometry reference equations to the GLI2012...

Research

Novel end points for clinical trials in young children with cystic fibrosis

Cystic fibrosis (CF) lung disease commences early in the disease progression and is the most common cause of mortality.

Research

Genetic and epigenetic susceptibility to early life infection

To date there have been relatively few studies on genetic determinants of susceptibility to neonatal infection and many of these have methodological...