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The aim of our study was to investigate whether CBL0137 has potential as a therapeutic and chemopotentiating compound in MLL-r leukemia

Our approach to hematopoietic progenitor cells mobilization resulted in highly effective HPC harvest in children and adolescents with high-risk cancers

Children with Primary Central Nervous System Lymphoma and no immunodeficiency have a good outcome

Although neurocognitive, psychological and behavioural problems were noted for some patients during medical review, only 20% of patients were formally assessed.

This study advances our understanding of drug resistance in T-ALL and provides new markers for patient stratification.

This study contributes to our understanding of the genetic diversity of NMC, an important step towards finding therapeutic targets for a disease that is...

Acute Lymphoblastic Leukemia (ALL) occurring in the first year of life is rare.

The hallmarks of many haematological malignancies and solid tumours are chromosomal translocations, which may lead to gene fusions.

In T-cell acute lymphoblastic leukemia (T-ALL) cytogenetic alterations juxtapose the LIM-domain-only-2 gene (LMO2) with T-cell receptor loci.

Glucocorticoids (GCs) are among the most important drugs for the treatment of acute lymphoblastic leukaemia (ALL).