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Dahlem ConferenceThere is increasing evidence that the functional state of the immune system at birth is predictive of the kinetics of immune maturation in early infancy.
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Evaluation of impact of 23 valent pneumococcal polysaccharide vaccine following 7 valent pneumococcal conjugate vaccine in Australian Indigenous children.Background: High incidence and serotype diversity of invasive pneumococcal disease (IPD) in Indigenous children in remote Australia led to rapid introduction of
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Th2-associated immunity to bacteria in asthma in teenagers and susceptibility to asthmaBacterial colonisation of the airways is associated with increased risk of childhood asthma
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Childhood atopy and mental health: a prospective, longitudinal investigationFindings are the first linking atopy (measured by both parent report and objective verification) with increased vulnerability to affective and anxiety problems
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Gene polymorphisms, breast-feeding, and development of food sensitization in early childhoodThe effect of breast-feeding on the development of allergic disease is uncertain
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Hospitalisation for bronchiolitis in infants is more common after elective caesarean deliveryThe authors previously reported an increased risk of hospitalisation for acute lower respiratory infection up to age 2 years in children delivered by...
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Toll-like receptor 7 function is reduced in adolescents with asthmaAnti-viral innate immune responses may be impaired in asthma, although the mechanisms are not well understood.
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Population-based estimates of the effectiveness of pneumococcal vaccination in AustraliaAustralia’s Childhood Immunisation Register (ACIR) is one of only a handful of national immunisation registers world-wide.
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Epigenome-wide analysis links SMAD3 methylation at birth to asthma in children of asthmatic mothersWe sought to assess whether the trajectory to asthma begins already at birth and whether epigenetic mechanisms, contribute to asthma inception.
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Streptococcus pneumoniae colonization of the nasopharynx is associated with increased severity during respiratory syncytial virus infection in young childrenThe present study aimed to clarify the effect of viral and bacterial co-detections on disease severity during paediatric acute respiratory infection (ARI).