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We investigated the suggestion that otitis-prone children have an impaired antibody response in the context of pneumococcal vaccination.
Reviewed in this article these studies have identified positive association at 21 genes with association at five of these replicated in independent populations.
Vaccines including conserved antigens from Streptococcus pneumoniae & nontypeable Haemophilus influenzae have the potential to reduce of otitis media.
Otitis media (OM) is a common childhood disease characterised by middle ear inflammation following infection
In Australia the 7-valent pneumococcal conjugate vaccine (PCV7) is administered at 2, 4 and 6 months of age, with no booster dose.
Streptococcus pneumoniae, Moraxella catarrhalis, and nontypeable Haemophilus influenzae is associated with otitis media
Haemophilus haemolyticus is often incorrectly categorized as nontypeable Haemophilus influenzae (NTHI) upon culture. PCR analyses of 266 NTHI-like nasopharyngea
Demonstrate mucosal bacterial infection in children with otitis media with effusion (OME).
Honorary Emeritus Fellow
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