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Research
Defective respiratory tract immune surveillance in asthma : A primary causal factor in disease onset and progressionThe relative importance of respiratory viral infections vs inhalant allergy in asthma pathogenesis is the subject of ongoing debate.
Research
Rhinovirus exacerbates house-dust-mite induced lung disease in adult miceIn this study, we combined human-rhinovirus infection with a clinically relevant mouse model of aero-allergen exposure using house-dust-mite in an attempt to...
News & Events
ORIGINS Project shines light on Early Childhood DevelopmentA collaboration between The Kids Research Institute Australia and Joondalup Health Campus is poised to be a game-changer for early childhood development.
News & Events
WA researchers lead global centre to eliminate childhood asthmaAn ambitious project that could stop children developing asthma is the centrepiece of a new world-class respiratory research centre launched in Perth.
Research
Viral infections and atopy in asthma pathogenesis: New rationales for asthma prevention and treatmentProspective birth cohort studies tracking asthma initiation and consolidation in community cohorts have identified viral infections occurring against a...
Research
Vitamin D 3 deficiency enhances allergen-induced lymphocyte responses in a mouse model of allergic airway diseaseIn this study, using a mouse model, we determined whether vitamin D deficiency in utero and during early life modulated the severity of asthma.
Research
Severity and persistence of asthma and mental health: a birth cohort studyThe goal of the current study was to investigate asthma and mental health among youth in the community.
Research
Regulatory role of IL10 genetic variations in determining allergen-induced TH2 cytokine responses in childrenInterleukin-10 is a key immunomodulatory cytokine the principal function of which is to limit the magnitude of immune response.
Research
Do early-life viral infections cause asthma?Epidemiologic associations between viral lower respiratory infections (LRIs) and asthma in later childhood are well known
Research
UV exposure and protection against allergic airways diseaseAsthma is a chronic inflammatory disease of the small and large conducting airway mucosa characterised by Th2 cell immunity.