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Research

Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics

Consistent with the original model of prebiotics, but aware of the latest scientific and clinical developments, the panel updated the definition of a prebiotics

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Twenty-Five Year Survival of Children with Intellectual Disability in Western Australia

To investigate survival up to early adulthood for children with intellectual disability and compare their risk of mortality with that of children without intellectual disability.

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Determinants of early-life lung function in African infants

To assess the determinants of early lung function in African infants.

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Altered regulatory T-cell fractions and Helios expression in clinically isolated syndrome: clues to the development of multiple sclerosis

These results indicate that T regulatory (Treg) and follicular T regulatory (Tfr) impairment is an early feature in MS.

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Creating community indicators for early childhood development: challenges and innovations from the kids in communities study

The community (or neighbourhood) is seen as a potential point of intervention for improving early childhood development outcomes through place-based approaches targeting all children. Yet there are insufficient robust data to guide policy and practice. Developing community factors for early childhood development is one way to facilitate more informed, evidence-based community action. This paper discusses the methodological learnings from the Kids in Communities Study, an Australian investigation into community-level factors important for early childhood development, including some of the challenges and innovations associated with the measurement and development of indicators.

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Fetal alcohol spectrum disorder in Australia: Practice guidelines for diagnosis and management

Fetal alcohol spectrum disorder in Australia: Practice guidelines for diagnosis and management

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Expanding the clinical picture of the MECP2 Duplication syndrome

People with two or more copies of MECP2 gene, located at Xq28, share clinical features and a distinct facial phenotype called MECP2 Duplication syndrome.

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Influence of the day care, home and neighbourhood environment on young children's physical activity and health: protocol for the PLAYCE observational study

The PLAYCE study will empirically investigate the relative and cumulative influence of the day care, and home environment on preschoolers’ physical activity

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Recurrent MET fusion genes represent a drug target in pediatric glioblastoma

We identified previously unidentified gene fusions involving the MET oncogene in pediatric glioblastoma

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Immunodominant T-cell epitopes in the VP1 capsid protein of rhinovirus species A and C

Our results indicate a dissociation between the antibody and T-cell responses to rhinoviruses