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Early detection of lung function abnormalities in young children with cystic fibrosisIn this review, we have examined the role of lung function testing in infants and preschool children with CF.
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Airway Epithelial Cells Condition Dendritic Cells to Express Multiple Immune Surveillance GenesAEC-conditioned DC showed selective upregulation of chemokines that recruit Th1 cells, but minimal change in chemokines linked to Th2 cell recruitment.
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Peptides targeting the mitogen-activated protein kinase pathway (JNK/JUN) fail to reduce infarct volume after permanent MCAO in sprague dawley ratsIn this study we have assessed the ability of two TAT-fused peptides to reduce infarct volume and improve functional outcome following permanent ischaemia.
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Symptomatic viral infection is associated with impaired response to treatment in children with acute asthmaThe objective of this study was to examine the influence of viral respiratory infection (VRI) on treatment response in acute asthma in children.
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Kawasaki disease, childhood allergy and the hygiene hypothesisKawasaki disease is characterized by increased inflammation
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The global epidemiology of impetigo: A systematic review of the population prevalence of impetigo and pyodermaWe conducted a comprehensive, systematic review of the global childhood population prevalence of impetigo and the broader condition pyoderma.
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Impact of adolescent peer aggression on later educational and employment outcomes in an Australian cohortThis study used prospective birth cohort data to analyse the relationship between peer aggression at 14 years of age and educational and employment outcomes...
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Evolution, Evidence and Effect of Secondary Prophylaxis Against Rheumatic FeverThe association between group A streptococcal infection and rheumatic fever (RF) was established in the early 20th century.
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Assessment of cardiometabolic risk in children in population studies: underpinning developmental origins of health and disease mother–offspring cohort studiesPregnancy and birth cohorts have been utilised extensively to investigate the developmental origins of health and disease, particularly in relation to...
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Maternal vitamin D deficiency alters fetal brain development in the BALB/c mouse.Prenatal exposure to vitamin D is thought to be critical for optimal fetal neurodevelopment, yet vitamin D deficiency is apparent in a growing proportion of...