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GWAS results provide firm confirmation for the importance of antigen presentation and the regulation of IFNγ in determining the outcome of Leishmania infections

Our data set provides a useful reference point for genomic studies on Aboriginal Australians

There is insufficient evidence available to determine whether these organisms are pathogens, commensals or contribute indirectly to the pathogenesis of OM

Amphotericin B provides improved therapy for visceral leishmaniasis (VL) caused by Leishmania donovani

We confirmed the strong association between high DAT and/or rK39 titers and progression to disease among asymptomatic subjects

To understand how HLA-DR contributes to disease pathogenesis, we examined expression at the protein level in circulating myeloid and lymphoid cells of VL patients

Reviewed in this article these studies have identified positive association at 21 genes with association at five of these replicated in independent populations.

Here we employ whole blood assays to evaluate human cytokine responses to 11 of these antigens, in comparison to known defined and crude antigen preparations.

To investigate whether variants in cardiovascular candidate genes, some of which have been previously associated with type 2 diabetes (T2D), diabetic...

Multiple sclerosis is a common disease of the central nervous system in which the interplay between inflammatory and neurodegenerative processes typically...