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Gene dysregulation in acute HIV-1 infection – early transcriptomic analysis reveals the crucial biological functions affectedTranscriptomic analyses from early human immunodeficiency virus (HIV) infection have the potential to reveal how HIV causes widespread and lasting damage to biological functions, especially in the immune system. Previous studies have been limited by difficulties in obtaining early specimens.
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The effect of the COVID-19 pandemic on paediatric anaesthesia research as evidenced by the contrasting recruitment experiences of centres in Australia and ScotlandAt two hospitals in Western Australia, we conducted a prospective, open-label, randomised, controlled trial of 240 patients undergoing tonsillectomy to investigate the effect of chewing a confectionery jelly snake on postoperative nausea and vomiting. The results were published in Anaesthesia Critical Care & Pain Medicine. Recruitment for this study was completed uneventfully between July 2018 and August 2019.
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Rhinovirus C is associated with wheezing and rhinovirus A is associated with pneumonia in hospitalized children in MoroccoWe aimed to describe the distribution of RV species and associations between RV species and clinical features in children hospitalized with clinically severe pneumonia in Morocco
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Cannabis-induced attenuated psychotic symptoms: implications for prognosis in young people at ultra-high risk for psychosisThis study examined UHR transition risk as a function of cannabis use characteristics which vary largely between people, due to a variety of factors.
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Identification and characterization of a dendritic cell precursor in parenchymal lung tissueThis is the first study to describe a pulmonary precursor cell for dendritic cells in lung tissue
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The Promise of Electroencephalography for Advancing Diagnosis and Treatment in Neurodevelopmental DisordersNeurodevelopmental disorders (NDDs), such as autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder, and intellectual disability (ID), commonly emerge during early development and impact functioning across cognitive, social-emotional, communication, and sensorimotor domains.
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Severe winter asthma exacerbations can be prevented by omalizumab, but there is no carryover effect.Recurrent severe asthma exacerbations are associated with decreased lung growth or accelerated loss of long function and add substantially to cost and morbidity
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Outcomes of an international workshop on preconception expanded carrier screening: Some considerations for governmentsConsideration of expanded carrier screening has become an emerging issue for governments.
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Validity and Reliability of the Early Development Instrument in IndonesiaThis study finds that the EDI shows moderate validity and reliability in poor communities in Indonesia and highlights some of the difficulties associated with adapting western instruments for non-western cultures and contexts.
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Liquor landscapes: Does access to alcohol outlets influence alcohol consumption in young adults?Longitudinal analyses showed that for each increase in liquor stores over time, alcohol consumption increased