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Research

Epigenetic Age Acceleration in Adolescence Associates with BMI, Inflammation, and Risk Score for Middle Age Cardiovascular Disease

Accelerated epigenetic age in adolescence was associated with inflammation, BMI measured 5 years later, and probability of middle age cardiovascular disease

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Pain after discharge following head and neck surgery in children

Adenotonsillectomy patients represent the biggest challenge in postoperative pain management of the head and neck surgeries evaluated

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Ultraviolet radiation, vitamin D and multiple sclerosis

Recent work highlights both vitamin D and non-vitamin D effects on cellular immunity that suggests that higher levels of sun exposure and/or vitamin D status...

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Febrile seizures following measles and varicella vaccines in young children in Australia

Febrile seizures (FS) are common in childhood with incidence peaking in the second year of life when measles and varicella-containing vaccines are administered.

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Switching from tobacco cigarettes in very early pregnancy: The effects of in utero e-cigarette exposure on mouse offspring neurodevelopment and behaviour

Electronic cigarettes (e-cigarettes) are often perceived to be safer than smoking, which has led to some women switching to e-cigarettes during pregnancy. However, the effects of switching from smoking to e-cigarettes on both pregnancy outcomes and the foetus are largely unknown. This study aimed to investigate the effects of switching from tobacco smoking to e-cigarette use in very early pregnancy on birth outcomes, neurodevelopment and behaviour of the offspring.

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Quality of Childcare Influences Children's Attentiveness and Emotional Regulation at School Entry

Among children using formal childcare, those who experienced higher-quality relationships were better able to regulate their attention and emotions as they...

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Breastfeeding Duration and Residential Isolation amid Aboriginal Children in Western Australia

The objective of this study was to examine the factors that impact on breastfeeding duration among Western Australia Aboriginal children. We hypothesised...

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The current state of play of rodent models to study the role of vitamin D in UV-induced immunomodulation

Ultraviolet radiation (UVR) from sunlight is immunomodulatory and the main source of vitamin D for humans.

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Age at surgery and outcomes of an undescended testis

We investigated the prevalence of UDT and examined rates of surgery and age at surgery in an Australian population.

Research

Radiographic and visual response to the type II RAF inhibitor tovorafenib in children with relapsed/refractory optic pathway glioma in the FIREFLY-1 trial

Due to their anatomical locations, optic pathway gliomas (OPGs) can rarely be cured by resection. Given the importance of preserving visual function, we analyzed radiological and visual acuity (VA) outcomes for the type II RAF inhibitor tovorafenib in the OPG subgroup of the phase 2 FIREFLY-1 trial.