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Research

Multi-institutional analysis of treatment modalities in basal ganglia and thalamic germinoma

Central nervous system germinomas are treatment-sensitive tumors with excellent survival outcomes. Current treatment strategies combine chemotherapy with radiotherapy (RT) in order to reduce the field and dose of RT. Germinomas originating in the basal ganglia/thalamus have proven challenging to treat given their rarity and poorly defined imaging characteristics. Craniospinal, whole brain, whole ventricle, and focal RT have all been utilized; however, the best treatment strategy remains unclear.

Research

Immunisation with the BCG and DTPw vaccines induces different programs of trained immunity in mice

In addition to providing pathogen-specific immunity, vaccines can also confer nonspecific effects (NSEs) on mortality and morbidity unrelated to the targeted disease. Immunisation with live vaccines, such as the BCG vaccine, has generally been associated with significantly reduced all-cause infant mortality. In contrast, some inactivated vaccines, such as the diphtheria, tetanus, whole-cell pertussis (DTPw) vaccine, have been controversially associated with increased all-cause mortality especially in female infants in high-mortality settings.

Research

Crowding and other strong predictors of upper respiratory tract carriage of otitis media-related bacteria

Streptococcus pneumoniae, Moraxella catarrhalis, and nontypeable Haemophilus influenzae is associated with otitis media

Research

Community Development Coordinator Role Consultation: Consultation Report

This report will outline the theory and evidence base for Community Development and Community Engagement, report on consultation activities and findings

Research

Indigenous young people's resilience and wellbeing

Carrington Shepherd PhD Honorary Research Associate Honorary Research Associate Areas of research expertise: Population health; Aboriginal and Torres

People

Professor Ben Jackson

Head, Brain and Behaviour Research

News & Events

New Funding Supports ORIGINS’ Expansion into Early Childhood Research

The ORIGINS Project has been named as a key beneficiary of the Stan Perron Charitable Foundation Research People & Platform round for 2023.

News & Events

Farewell Marie-Anne

After living in Perth for the past three years, Dr Marie-Anne Burckhardt has headed back home to continue her type 1 diabetes research.

Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis.

Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis. Abstract Although destructive airway

Alpha-1 Antitrypsin Mitigates the Inhibition of Airway Epithelial Cell Repair by Neutrophil Elastase

Alpha-1 Antitrypsin Mitigates the Inhibition of Airway Epithelial Cell Repair by Neutrophil Elastase Abstract Neutrophil elastase (NE) activity is