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Research
UV inhibits allergic airways disease in mice by reducing effector CD4 T cellsIn human asthma, and experimental allergic airways disease in mice, antigen-presenting cells and CD4(+) effector cells at the airway mucosa orchestrate, and CD4
Research
Decreased fibronectin production significantly contributes to dysregulated repair of asthmatic epitheliumIn human asthma, and experimental allergic airways disease in mice, antigen-presenting cells and CD4(+) effector cells at the airway mucosa orchestrate, and CD4
Research
Long-term derangement of antigen presenting cell populations in the respiratory tract following Influenza A infectionThis project investigates how different populations of cells within the respiratory tract immune system are altered during a viral infection.
News & Events
WA researchers lead global centre to eliminate childhood asthmaAn ambitious project that could stop children developing asthma is the centrepiece of a new world-class respiratory research centre launched in Perth.
News & Events
ORIGINS Project shines light on Early Childhood DevelopmentA collaboration between The Kids Research Institute Australia and Joondalup Health Campus is poised to be a game-changer for early childhood development.
News & Events
New lease on life for DartanyonTwo years on, Michelle and Dartanyon’s health and quality of life have significantly improved. We caught up with Michelle to hear about their journey since we first met them.
Research
Blocking Notch3 Signaling Abolishes MUC5AC Production in Airway Epithelial Cells from AsthmaticsWe demonstrate that NOTCH3 is a regulator of MUC5AC production
Research
Airway Interleukin-33 and type 2 cytokines in adult patients with acute asthmaAirway interleukin-33 is associated with type-2 cytokines in naturally occurring asthma exacerbations in adults
Research
Asthma is responsible for considerable global morbidity and health-care costs. Substantial progress was made against key outcomes such as hospital admissions with asthma and mortality in the 1990s and early 2000s, but little improvement has been observedWe aim to provide our view of where we are and where we need to go as a community of clinicians and researchers who tackle the public health problem of asthma.
Research
A genome-by-environment interaction classifier for precision medicine: personal transcriptome response to rhinovirus identifies children prone to asthma exacerbationsTo introduce a disease prognosis framework enabled by a robust classification scheme derived from patient-specific transcriptomic response to stimulation.