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Our result highlighted that miRNA-target gene network contributes to human disease genetics in a cell type-specific manner

Epigenetic changes at the GFI1 were linked to smoking exposure in-utero/in-adulthood and robustly associated with cardio-metabolic risk factors

A better understanding of the innate immune responses by CF airway epithelial cells is needed to identify why viral infections are more severe in CF

A comprehensive in depth gene expression/regulation profile in Mycobacterium tuberculosis-infected macrophages

We hypothesised that the performance of variant prioriisation tools may vary by disease phenotype.

Epigenetically regulated genes have a great theranostic potential, especially in tumors with no apparent driver mutations.

Orm1 is induced in response to hepatic injury and executes liver regeneration by activating cell cycle progression in hepatocytes

CAGE in combination with single-molecule sequencing technology allows mapping of TSSs and genome-wide capture of promoter activities state cell populations.

CAGEd-oPOSSUM can identify transcription factors that act as key regulators of genes involved in specific mammalian cell and tissue types

Increases in ASD was not only limited to advancing paternal or maternal age alone but also to differences parental age including younger or older similarly age