Search

Airway epithelial cells act through multiple mechanisms to function as an important component of the pulmonary defence strategy that is crucial...

Atopic asthma, which is at its highest prevalence during childhood/young adulthood, represents the main focus of this review.

Airways hyperresponsiveness (AHR) is one of the major clinical features of allergic airways disease including allergic asthma

We have recently published a paper identifying precursor populations in peripheral lung (2017), and have also discovered that these populations can be found in multiple tissues.

This study will identify how the immune system contributes to neurodevelopmental outcomes and will investigate the use of an agent from traditional medicines.

This study will investigate the why disease is worse in infants and how early life viral infection impacts the developing immune system.

This is a strategic “pilot” project in which we are seeking basic information on the immune cell content of gestational tissues.

This project investigates how different populations of cells within the respiratory tract immune system are altered during a viral infection.

Dysbiosis refers to a reduction in microbial diversity, combined with a loss of beneficial taxa, and an increase in pathogenic microorganisms. Dysbiosis of the intestinal microbiota can have a substantial effect on the nervous and immune systems, contributing to the onset of several inflammatory diseases.

Incomplete maturation of immune regulatory functions at birth is antecedent to the heightened risk for severe respiratory infections during infancy. Our forerunner animal model studies demonstrated that maternal treatment with the microbial-derived immune training agent OM-85 during pregnancy promotes accelerated postnatal maturation of mechanisms that regulate inflammatory processes in the offspring airways.