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Airway epithelial cells act through multiple mechanisms to function as an important component of the pulmonary defence strategy that is crucial...

Atopic asthma, which is at its highest prevalence during childhood/young adulthood, represents the main focus of this review.

Airways hyperresponsiveness (AHR) is one of the major clinical features of allergic airways disease including allergic asthma

Our findings suggest that the proportion of degranulated basophils can also be associated with recurrent exacerbations

The co-exposure responses in the Th2high BN incorporated type I interferon/Th1, alternative macrophage activation/Th2 and Th17 signatures

In this review, we discuss recent mechanistic studies casting further light on how the expression of sex hormones may influence the innate and adaptive immune system

Respiratory IgE-sensitization to innocuous antigens increases the risk for developing diseases such as allergic asthma.

Role for CD103 in the pathogenesis of experimental allergic airways disease in BALB/c mice through local control of CD4+ T cell and DC subset recruitment

In addition to its role in blocking TH2 effector activation in the late-phase allergic response, IL-10 is a known IgG1 switch factor

Head, Pregnancy and Early Life Immunology