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This project investigates how different populations of cells within the respiratory tract immune system are altered during a viral infection.

This is a strategic “pilot” project in which we are seeking basic information on the immune cell content of gestational tissues.

This study will investigate the why disease is worse in infants and how early life viral infection impacts the developing immune system.

This study will identify how the immune system contributes to neurodevelopmental outcomes and will investigate the use of an agent from traditional medicines.

Head, Pregnancy and Early Life Immunology

We have recently published a paper identifying precursor populations in peripheral lung (2017), and have also discovered that these populations can be found in multiple tissues.

The expression pattern of FcεRI on DC and basophils differentiates asthmatic from non-asthmatic atopic children

Dysregulated expression of IFN-dependent pathways after respiratory viral infections is a defining immunophenotypic feature of AVB-susceptible infants

This protocol adapted an experimental animal model of disease for sensitization to ovalbumin during the immediate post-weaning period beginning at 21 days of age

We have demonstrated that a single dose of a closely related commensal can delay onset of NTHi otitis media in vivo