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Effects of Ser47-Point Mutation on Conformation Structure and Allergenicity of the Allergen of Der p 2, a Major House Dust Mite AllergenThe mutant Der p 2 had altered structure and reduced ability to stimulate pro-inflammatory responses and to bind IgE
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House Dust Mite Allergens: New Discoveries and Relevance to the Allergic PatientRecent findings on house dust allergens and their contribution to knowledge that will significantly impact current and future allergy treatments are appraised
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Western environment/lifestyle is associated with increased genome methylation and decreased gene expression in Chinese immigrants living in AustraliaChinese immigrants living in Australia for a longer period of time have increased overall genome methylation and decreased overall gene expression
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Chronic cat allergen exposure induces a Th2 cell-dependent IgG4 response related to low sensitizationThis study evaluated the relationship between cat allergen–specific biomarkers in adults with cat allergy with and without cat ownership.
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Antibacterial antibody responses associated with the development of asthma in house dust mite-sensitised and non-sensitised childrenWe aimed to measure the antibody development to 2 bacteria in a birth cohort at high risk of allergic disease, and to assess which responses are asthma-linked.
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Structural and IgE binding analyses of recombinant Der p 2 expressed from the hosts Escherichia coli and Pichia pastorisThe house dust mite allergen Der p 2 is one of the most important indoor allergens associated with allergic disease.
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House dust mite allergens in asthma and allergyIgE antibodies in house dust mite (HDM) allergy follow a predictable pattern. Half are directed against two dominant allergens and the remainder largely against
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Investigations into the role of ST2 in acute asthma in childrenThis study investigated the potential role of ST2 in children with acute asthma.
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Clinical Management of Staphylococcus aureus Bacteremia in Neonates, Children, and AdolescentsStaphylococcus aureus is a common cause of community and health care-associated bacteremia, with authors of recent studies estimating the incidence of S aureus bacteremia (SAB) in high-income countries between 8 and 26 per 100 000 children per year. Despite this, <300 children worldwide have ever been randomly assigned into clinical trials to assess the efficacy of treatment of SAB.
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RSV prophylaxis use in high-risk infants in Western Australia, 2002-2013: a record linkage cohort studyThe monoclonal antibody, palivizumab is licensed for use in high-risk infants to prevent severe illness caused by respiratory syncytial virus (RSV). The level of its use and compliance with current jurisdictional guidelines which were amended in 2010, is unknown.