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Efficacy, Immunogenicity, and Safety Study of Clostridium difficile Toxoid Vaccine in Subjects at Risk for C. difficile Infection

Investigators: Camille Gibson, Fiona McDonald, Glady Perez, Jan Jones, Jane Jones, Jennifer Kent, Lisa Montgomery, Peter Richmond, Rachel West, Tabitha Woodman, Tanya Stoney

Project description

This study was investigating a trial vaccine that hoped to prevent Clostridium difficile Infection (CDI) in adults aged 50 years or greater who are at risk for CDI. Participants were placed into 1 of 2 risk groups that reflect the risk factors for developing CDI including previous and proposed hospitalisation and antibiotics use. Participants were to be followed for up to 3 years to determine the effectiveness of the vaccine in preventing CDI in these at risk adults.

Partners

  • Sanofi Pasteur