Investigators: André Schultz, Graham Hall, Ingrid Laing, Stacey Reinke, David Broadhurst
Aims: To use metabolomics to determine if urine can identify if children who wheeze as pre-schoolers will develop asthma.
Project description
Childhood asthma begins as wheeze (a whistling sound produced by the airways during breathing) during preschool age. By the age of 6, about 70% of children will outgrow their wheeze. However, it is not possible to determine who will outgrow their wheeze and who will not. For preschool children who experience symptoms severe enough to warrant a doctor’s visit, they are generally prescribed asthma medication that has long-term side effects. The aim of this study is to work out if urine can be used to identify if children who wheeze as pre-schoolers will develop asthma and gain a better understanding of disease mechanisms.
Collaborators
- Perth Children’s Hospital
- Edith Cowan University