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Discover . Prevent . Cure .

Development of a longer acting formulation of Penicillin G for the treatment and prevention of acute rheumatic fever and rheumatic heart disease

Investigators: Dianne Sika-Paotonu, Joe Kado, Jonathan Carapetis, Rebecca Trowman, Robert Hand

Partner: Novartis Institute for BioMedical Research

The most effective recommended treatment to prevent RHD requires monthly injections of penicillin. These injections are painful and difficult to administer and as such many patients do not adhere to their treatment plan. This projects aims to develop a longer acting formulation of penicillin, such that frequency of the injection can be increased up to 3-6 months. This will provide a practical, less painful method of treatment and vastly increase the number of patients being successfully treated.