Investigators: Anthony Kicic, Belinda Hales, Ingrid Laing
Human rhinovirus (HRV) is the most common pathogen detected in many childhood respiratory diseases. Emerging evidence suggested the importance of HRV-C species associated with acute asthma and induction of severe wheeze in children. However, traditional culture method has failed to produce sufficient HRV-C for downstream study. In order to study the mechanism of HRV-C induced respiratory diseases, we sought to emulate the technique of culturing HRV-C to achieve adequate amount of HRV-C for our experiment and development of treatment models.