Reports and Findings
Traditional markers modestly predict chronic kidney disease progression in Aboriginal and Torres Strait Islander people. Therefore, we assessed associations of cardiometabolic and inflammatory clinical biomarkers with kidney disease progression among Aboriginal and Torres Strait Islander people with and without diabetes.
To examine the longitudinal effects of dog ownership and dog walking on self-reported and objective measures of physical function in mid- to older-aged adults.
Our aim is to improve the emergency transfer of very ill babies by the NETS WA team such that it better supports parents and enhances infants’ recovery and long-term outcomes.
To explore trends in the receipt of commonly prescribed medications (beyond insulin) in people with type 1 diabetes in Australia, including polypharmacy, and to investigate socioeconomic disparities across these trends.
Non-coercive 'nudge' interventions have shown the potential to promote health behaviours. This study aimed to evaluate the impact of nudge interventions on COVID-19/influenza vaccine uptake among children with medically at-risk conditions.
Hepatitis B (HBV) prevalence is very high in pregnant women in the Dolpa district of Nepal, a region characterised by a remote geographic landscape and low vaccination coverage. Using mathematical modelling, we evaluated the impact of third-trimester tenofovir disoproxil fumarate (TDF) prophylaxis on HBV burden and estimated the time required to achieve HBV elimination in Dolpa.
LGBTIQA + people experience intimate partner violence (IPV) at higher rates than non-LGBTIQA + people but under-utilize professional support services, and the reasons for this are poorly understood. This study examined IPV experiences, recognition of IPV, service utilization, and support needs among a self-selected sample of 523 LGBTIQA + adults in Western Australia.
In Australia, infants have the highest rate of child protection involvement. Many jurisdictions in Australia and internationally have introduced policies for prenatal planning and support, however little is known about outcomes of infants reported prenatally. This study is the first to use cross-jurisdictional, individual-record data to examine child protection pathways associated with prenatal and infant reports.
T cells engineered to express chimeric antigen receptors (CARs) are a promising modality to treat refractory cancers. CD19 CAR-T therapy has achieved remarkable responses in against B-cell lymphomas, however, challenges persist for acute myeloid leukemia (AML) and solid malignancies. B7H3 is an immune regulatory molecule that is highly expressed in various tumor cells. Its abnormal expression in acute AML and esophageal squamous cell carcinoma (ESCC) is closely related to tumor progression.
Efforts to promote adolescent wellbeing are of increasing global interest. Although the ability to measure wellbeing is essential for identifying disparities between and within populations, and for tracking progress in improving wellbeing, the best way to measure this elusive concept in adolescents is unclear.