Theplatform trialinCOVID-19 priming andBOOsting (PICOBOO): The reactogenicity of nine licensed COVID-19 vaccines delivered in immunocompetent adults

Citation:
McLeod C, Dymock M, Flanagan KL, ……..  Tjiam MC, Blyth CC, Subbarao K, ……. Wadia U, Thornton RB, Ellis Z, Williams P, McKenzie A, Marsh JA, Foulis C, …….. Richmond P. Theplatform trialinCOVID-19 priming andBOOsting (PICOBOO): The reactogenicity of nine licensed COVID-19 vaccines delivered in immunocompetent adults. Vaccine. 2026;92.

Keywords:
Booster vaccination; COVID-19; Clinical trial; Reactogenicity; Safety

Abstract:
PICOBOO is a randomised, Bayesian adaptive trial evaluating immunogenicity and reactogenicity of licensed COVID-19 vaccines in immunocompetent individuals aged >12 years. We present reactogenicity data for nine vaccines administered as additional doses within adult strata based on age cohort and primary vaccination regimen.