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Toxic in vitro effects of flavoured-air inhalers containing essential oils in differentiated human nasal epithelial cells at air–liquid interface

Citation:
Larcombe AN, Catchpole EE, Hopper P, Stanley S, Kicic A, Landwehr KR. Toxic in vitro effects of flavoured-air inhalers containing essential oils in differentiated human nasal epithelial cells at air–liquid interface. Arch Toxicol. 2026.

Keywords:
Airway epithelial cells; Air–liquid interface; Essential oils; Flavoured-air; Respiratory toxicity

Abstract:
Flavoured-air inhalers containing essential oils are marketed as safe, natural alternatives to smoking and vaping, yet their potential respiratory toxicity remains effectively unexamined. Manufacturers claim safety based on "100% natural" ingredients, despite evidence that essential oil inhalation can cause adverse respiratory effects.