Keywords:
Pneumococcal infectons; microbiology; penicillin; vaccines; streptococcus pneumoniae; genetics; immunology; transmission; geographic mapping
Abstract:
Streptococcus pneumoniae is a leading cause of pneumonia and meningitis worldwide. Many different serotypes co-circulate endemically in any one location. The extent and mechanisms of spread and vaccine-driven changes in fitness and antimicrobial resistance remain largely unquantified.