Comparing Skin and Serum Testing to Direct Challenge Outcomes in Children With beta-Lactam Allergies

There is a scarcity of prospective studies investigating the relative roles of skin prick and intradermal testing, serum specific IgE, and extended oral challenges in diagnosing children with reported β-lactam allergies.

Citation:
Lucas M, von Ungern-Sternberg BS, Arnold A, ……. Sommerfield D, Murray K, Rueter K. Comparing Skin and Serum Testing to Direct Challenge Outcomes in Children With beta-Lactam Allergies. J Allergy Clin Immunol Pract. 2024.

Keywords:
Antibiotic allergy; Delabeling; Pediatrics; Relabeling; β-Lactam

Abstract:
There is a scarcity of prospective studies investigating the relative roles of skin prick and intradermal testing, serum specific IgE, and extended oral challenges in diagnosing children with reported β-lactam allergies.