Keywords:
Early-life; Host-microbe; Interactions; Microbial-Immune priming; Microbiome; Spatial transcriptomics
Abstract:
Modern precision sequencing techniques have established humans as a holobiont that live in symbiosis with the microbiome. Microbes play an active role throughout the life of a human ranging from metabolism and immunity to disease tolerance. Hence, it is of utmost significance to study the eukaryotic host in conjunction with the microbial antigens to obtain a complete picture of the host-microbiome crosstalk.