Skip to content
The Kids Research Institute Australia logo

Determination of Tr1 cell populations correlating with distinct activation states in acute IAV infection

Type I regulatory (Tr1) cells are defined as FOXP3-IL-10-secreting clusters of differentiation (CD4+) T cells that contribute to immune suppression and typically express the markers LAG-3 and CD49b and other co-inhibitory receptors. These cells have not been studied in detail in the context of the resolution of acute infection in the lung.

Citation:
Abbott CA, Freimayer EL, Tyllis TS, ……. Pederson SM, Qu Z, Armstrong M, et al. Determination of Tr1 cell populations correlating with distinct activation states in acute IAV infection. Mucosal Immunol. 2023

Abstract:
Type I regulatory (Tr1) cells are defined as FOXP3-IL-10-secreting clusters of differentiation (CD4+) T cells that contribute to immune suppression and typically express the markers LAG-3 and CD49b and other co-inhibitory receptors. These cells have not been studied in detail in the context of the resolution of acute infection in the lung.